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skyn ICELAND Dissolving Microneedle Eye Patches with Hyaluronic Acid & Peptides: to Hydrate, Firm and Smooth Fine Lines (1 Pack)

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Li,Y.; Tan,O.; Brass,R.; Weiss,J.L.; Huang,D. Ophthalmology 2012, 119, 2425–2433. doi:10.1016/j.ophtha.2012.06.023

Zhang,J.; Wang,Y.; Jin,J.Y.; Degan,S.; Hall,R.P.; Boehm,R.D.; Jaipan,P.; Narayan,R.J. JOM 2016, 68, 1128–1133. doi:10.1007/s11837-016-1841-1Ammar,M.J.; Hsu,J.; Chiang,A.; Ho,A.C.; Regillo,C.D. Curr.Opin.Ophthalmol. 2020, 31, 215–221. doi:10.1097/icu.0000000000000657

Maulvi,F.A.; Shetty,K.H.; Desai,D.T.; Shah,D.O.; Willcox,M.D.P. Int.J.Pharm. 2021, 608, 121105. doi:10.1016/j.ijpharm.2021.121105 deGroot,A.M.; Platteel,A.C.M.; Kuijt,N.; vanKooten,P.J.S.; Vos,P.J.; Sijts,A.J.A.M.; vanderMaaden,K. Front.Immunol. 2017, 8, 10.3389/fimmu.2017.01789. doi:10.3389/fimmu.2017.01789Aung,N.N.; Ngawhirunpat,T.; Rojanarata,T.; Patrojanasophon,P.; Pamornpathomkul,B.; Opanasopit,P. Int.J.Pharm. 2020, 586, 119508. doi:10.1016/j.ijpharm.2020.119508

Datta et al. fabricated a lens-shaped MN patch of PVP for rapid corneal delivery of the macromolecular drug cyclosporine A (CsA) applied against uveitis, corneal injuries, vernal keratocojunctivitis, and other diseases with underlying inflammatory processes. Due to the composition, the MNs degraded and entirely dissolved within 60 s. The ex vivo experiments on pig excised cornea showed that, in comparison to Cyclomune eye drops, the application of the MNs resulted in higher values of drug flux and retention. CsA was evenly distributed within interior parts of the eye [187]. There are several different types of dissolving microneedle patches (and more coming out every day), but the two types specifically designed for acne-prone skin target blind pimples and post-inflammatory hyperpigmentation. Qiu,Y.; Li,C.; Zhang,S.; Yang,G.; He,M.; Gao,Y. Int.J.Pharm. 2016, 508, 1–9. doi:10.1016/j.ijpharm.2016.05.006

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Microneedles are extremely small, micro-sized needles designed to penetrate the outer layer of the skin. It is a common cosmetic procedure used to help improve skin imperfections such as wrinkles and acne scarring or just to rejuvenate the skin.

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